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Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland.
Godde, Nathan J; Sheridan, Julie M; Smith, Lorey K; Pearson, Helen B; Britt, Kara L; Galea, Ryan C; Yates, Laura L; Visvader, Jane E; Humbert, Patrick O.
Afiliação
  • Godde NJ; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.
  • Sheridan JM; ACRF Stem Cells and Cancer Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Smith LK; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.
  • Pearson HB; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.
  • Britt KL; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Metastasis Research Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
  • Galea RC; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.
  • Yates LL; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.
  • Visvader JE; ACRF Stem Cells and Cancer Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Humbert PO; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia; De
PLoS Genet ; 10(5): e1004323, 2014 May.
Article em En | MEDLINE | ID: mdl-24852022
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-fos / Sistema de Sinalização das MAP Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Mamárias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS Genet Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-fos / Sistema de Sinalização das MAP Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Mamárias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS Genet Ano de publicação: 2014 Tipo de documento: Article