[Rare tumors of the head and neck; on behalf of the REFCOR, the French Network of rare head and neck tumors]. / Cancers ORL rares et REFCOR, Réseau d'expertise français sur les cancers ORL rares.
Bull Cancer
; 101(5): 411-23, 2014 May 01.
Article
em Fr
| MEDLINE
| ID: mdl-24886891
ABSTRACT
Malignant tumors of the upper aerodigestive tract may be rare by their histology (sarcoma, variants of conventional squamous cell carcinomas) and/or location (sinuses, salivary glands, ear, of various histologies themselves). They represent less than 10% of head and neck neoplasms. The confirmation of their diagnosis often requires a medical expertise and sometimes biomolecular techniques complementary to classical histology and immunohistochemistry. Due to their location, their treatment often requires a specific surgical technique. Radiation therapy is indicated based on histoclinical characteristics common to other head and neck neoplasms but also incorporate grade. Further, the technique must often be adapted to take into account the proximity of organs at risk. For most histologies, chemotherapy is relatively inefficient but current molecular advances may allow to consider pharmaceutical developments in the coming years. The REFCOR, the French Network of head and neck cancers aims to organize and promote the optimal management of these rare and heterogeneous diseases, to promote research and clinical trials.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sarcoma
/
Neoplasias Otorrinolaringológicas
/
Neoplasias das Glândulas Salivares
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Carcinoma de Células Escamosas
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Doenças Raras
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
Fr
Revista:
Bull Cancer
Ano de publicação:
2014
Tipo de documento:
Article