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A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.
Fraser, Johanna E; Watanabe, Satoru; Wang, Chunxiao; Chan, Wing Ki Kitti; Maher, Belinda; Lopez-Denman, Adam; Hick, Caroline; Wagstaff, Kylie M; Mackenzie, Jason M; Sexton, Patrick M; Vasudevan, Subhash G; Jans, David A.
Afiliação
  • Fraser JE; Nuclear Signaling Laboratory, Department of Biochemistry and Molecular Biology, Monash University.
  • Watanabe S; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore.
  • Wang C; Nuclear Signaling Laboratory, Department of Biochemistry and Molecular Biology, Monash University.
  • Chan WK; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore.
  • Maher B; Nuclear Signaling Laboratory, Department of Biochemistry and Molecular Biology, Monash University.
  • Lopez-Denman A; Department of Microbiology and Immunology, University of Melbourne Department of Microbiology, La Trobe University, Bundoora.
  • Hick C; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.
  • Wagstaff KM; Nuclear Signaling Laboratory, Department of Biochemistry and Molecular Biology, Monash University.
  • Mackenzie JM; Department of Microbiology and Immunology, University of Melbourne.
  • Sexton PM; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.
  • Vasudevan SG; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore.
  • Jans DA; Nuclear Signaling Laboratory, Department of Biochemistry and Molecular Biology, Monash University.
J Infect Dis ; 210(11): 1780-91, 2014 Dec 01.
Article em En | MEDLINE | ID: mdl-24903662
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Antivirais / Dengue / Vírus da Dengue / Resposta a Proteínas não Dobradas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Infect Dis Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Antivirais / Dengue / Vírus da Dengue / Resposta a Proteínas não Dobradas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Infect Dis Ano de publicação: 2014 Tipo de documento: Article