Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.

Szyk, Agnieszka; Deaconescu, Alexandra M; Spector, Jeffrey; Goodman, Benjamin; Valenstein, Max L; Ziolkowska, Natasza E; Kormendi, Vasilisa; Grigorieff, Nikolaus; Roll-Mecak, Antonina

Szyk, Agnieszka; Deaconescu, Alexandra M; Spector, Jeffrey; Goodman, Benjamin; Valenstein, Max L; Ziolkowska, Natasza E; Kormendi, Vasilisa; Grigorieff, Nikolaus; Roll-Mecak, Antonina.

Afiliação

Szyk A; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.
Deaconescu AM; Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Spector J; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.
Goodman B; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.
Valenstein ML; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.
Ziolkowska NE; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.
Kormendi V; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.
Grigorieff N; Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Roll-Mecak A; Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA; National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA. Electronic address: antonina@mail.nih.gov.

Cell ; 157(6): 1405-1415, 2014 Jun 05.

Article em En | MEDLINE | ID: mdl-24906155

Assuntos

Acetiltransferases/química; Acetiltransferases/metabolismo; Microtúbulos/metabolismo; Acetilação; Domínio Catalítico; Cristalografia por Raios X; Humanos; Lisina/metabolismo; Microscopia Eletrônica de Transmissão; Modelos Moleculares; Tubulina (Proteína)/química; Tubulina (Proteína)/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetiltransferases / Microtúbulos Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article

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