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Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.
Dennison, S Moses; Anasti, Kara M; Jaeger, Frederick H; Stewart, Shelley M; Pollara, Justin; Liu, Pinghuang; Kunz, Erika L; Zhang, Ruijun; Vandergrift, Nathan; Permar, Sallie; Ferrari, Guido; Tomaras, Georgia D; Bonsignori, Mattia; Michael, Nelson L; Kim, Jerome H; Kaewkungwal, Jaranit; Nitayaphan, Sorachai; Pitisuttithum, Punnee; Rerks-Ngarm, Supachai; Liao, Hua-Xin; Haynes, Barton F; Alam, S Munir.
Afiliação
  • Dennison SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Anasti KM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Jaeger FH; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Stewart SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Pollara J; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
  • Liu P; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Kunz EL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Zhang R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Vandergrift N; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Permar S; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA Department of Molecular Ge
  • Ferrari G; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
  • Tomaras GD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA Department of Molecular Genet
  • Bonsignori M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
  • Michael NL; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Kim JH; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Kaewkungwal J; Tropical Hygiene, Mahidol University, Bangkok, Thailand.
  • Nitayaphan S; Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
  • Pitisuttithum P; Clinical Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Rerks-Ngarm S; Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
  • Liao HX; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
  • Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA alam0004@mc.duke.edu hayne00
  • Alam SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA alam0004@mc.duke.edu hayne002
J Virol ; 88(16): 9406-17, 2014 Aug.
Article em En | MEDLINE | ID: mdl-24920809
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD4 / Proteína gp120 do Envelope de HIV / HIV-1 / Vacinas contra a AIDS / Produtos do Gene env do Vírus da Imunodeficiência Humana / Galactosilceramidas / Epitopos Limite: Humans Idioma: En Revista: J Virol Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD4 / Proteína gp120 do Envelope de HIV / HIV-1 / Vacinas contra a AIDS / Produtos do Gene env do Vírus da Imunodeficiência Humana / Galactosilceramidas / Epitopos Limite: Humans Idioma: En Revista: J Virol Ano de publicação: 2014 Tipo de documento: Article