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Active-state model of a dopamine D2 receptor-Gαi complex stabilized by aripiprazole-type partial agonists.
Kling, Ralf C; Tschammer, Nuska; Lanig, Harald; Clark, Timothy; Gmeiner, Peter.
Afiliação
  • Kling RC; Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany; Department of Chemistry and Pharmacy, Computer Chemistry Center, Friedrich Alexander University, Erlangen, Germany.
  • Tschammer N; Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany.
  • Lanig H; Department of Chemistry and Pharmacy, Computer Chemistry Center, Friedrich Alexander University, Erlangen, Germany; Central Institute for Scientific Computing, Friedrich Alexander University, Erlangen, Germany.
  • Clark T; Department of Chemistry and Pharmacy, Computer Chemistry Center, Friedrich Alexander University, Erlangen, Germany; Centre for Molecular Design, University of Portsmouth, King Henry Building, Portsmouth, United Kingdom.
  • Gmeiner P; Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany.
PLoS One ; 9(6): e100069, 2014.
Article em En | MEDLINE | ID: mdl-24932547
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Conformação Proteica / Antipsicóticos / Dopamina / Receptores de Dopamina D2 / Quinolonas / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Conformação Proteica / Antipsicóticos / Dopamina / Receptores de Dopamina D2 / Quinolonas / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article