Attachment anxiety is related to Epstein-Barr virus latency.
Brain Behav Immun
; 41: 232-8, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24945717
ABSTRACT
Attachment theory provides a framework for understanding individual differences in chronic interpersonal stress. Attachment anxiety, a type of relationship insecurity characterized by worry about rejection and abandonment, is a chronic interpersonal stressor. Stress impacts cellular immunity, including herpesvirus reactivation. We investigated whether attachment anxiety was related to the expression of a latent herpesvirus, Epstein-Barr virus (EBV), when individuals were being tested for breast or colon cancer and approximately 1 year later. Participants (N=183) completed a standard attachment questionnaire and provided blood to assess EBV viral capsid antigen (VCA) IgG antibody titers. Individuals with more attachment anxiety had higher EBV VCA IgG antibody titers than those with less attachment anxiety. The strength of the association between attachment anxiety and antibody titers was the same at both assessments. This study is the first to show an association between latent herpesvirus reactivation and attachment anxiety. Because elevated herpesvirus antibody titers reflect poorer cellular immune system control over the latent virus, these data suggest that high attachment anxiety is associated with cellular immune dysregulation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos de Ansiedade
/
Ativação Viral
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Neoplasias da Mama
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Latência Viral
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Neoplasias do Colo
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Herpesvirus Humano 4
/
Apego ao Objeto
Tipo de estudo:
Etiology_studies
/
Qualitative_research
Limite:
Aged80
Idioma:
En
Revista:
Brain Behav Immun
Ano de publicação:
2014
Tipo de documento:
Article