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Development of a high-throughput assay for aldosterone synthase inhibitors using high-performance liquid chromatography-tandem mass spectrometry.
Yurek, David; Yu, Lan; Schrementi, James; Bell, Michael G; McGee, James; Kowala, Mark; Kuo, Ming-shang; Wang, Jian.
Afiliação
  • Yurek D; Tailored Therapeutics, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA. Electronic address: yurekda@lilly.com.
  • Yu L; Cardiometabolic Drug Hunting Teams, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
  • Schrementi J; Cardiometabolic Drug Hunting Teams, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
  • Bell MG; Medicinal Chemistry, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
  • McGee J; Quantitative Biology, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
  • Kowala M; Cardiometabolic Drug Hunting Teams, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
  • Kuo MS; Tailored Therapeutics, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
  • Wang J; Cardiometabolic Drug Hunting Teams, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
Anal Biochem ; 462: 44-50, 2014 Oct 01.
Article em En | MEDLINE | ID: mdl-24959941
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP11B2 / Espectrometria de Massas em Tandem / Ensaios de Triagem em Larga Escala / Inibidores das Enzimas do Citocromo P-450 Limite: Humans Idioma: En Revista: Anal Biochem Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP11B2 / Espectrometria de Massas em Tandem / Ensaios de Triagem em Larga Escala / Inibidores das Enzimas do Citocromo P-450 Limite: Humans Idioma: En Revista: Anal Biochem Ano de publicação: 2014 Tipo de documento: Article