KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-&#954;B and VEGF-C.

Yang, Moon Hee; Kim, Hyung Tae; Lee, Kyu Taek; Yang, Sera; Lee, Jong Kyoon; Lee, Kwang Hyuck; Rhee, Jong Chul

KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-κB and VEGF-C.

Yang, Moon Hee; Kim, Hyung Tae; Lee, Kyu Taek; Yang, Sera; Lee, Jong Kyoon; Lee, Kwang Hyuck; Rhee, Jong Chul.

Afiliação

Yang MH; Center for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kim HT; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Lee KT; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea ktcool.lee@samsung.com.
Yang S; Samsung Biomedical Research Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Lee JK; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Lee KH; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Rhee JC; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Anticancer Res ; 34(7): 3469-74, 2014 Jul.

Article em En | MEDLINE | ID: mdl-24982355

Assuntos

Arsenitos/farmacologia; Carcinoma Ductal Pancreático/tratamento farmacológico; Neoplasias Pancreáticas/tratamento farmacológico; Compostos de Sódio/farmacologia; Fator de Transcrição RelA/antagonistas & inibidores; Fator C de Crescimento do Endotélio Vascular/antagonistas & inibidores; Carcinoma Ductal Pancreático/metabolismo; Carcinoma Ductal Pancreático/patologia; Processos de Crescimento Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Humanos; Masculino; Invasividade Neoplásica; Neoplasias Pancreáticas/metabolismo; Neoplasias Pancreáticas/patologia; Fator de Transcrição RelA/metabolismo; Fator C de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

KML001; NF-κB; VEGF-C; invasion; pancreatic cancer; proliferation

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Compostos de Sódio / Arsenitos / Carcinoma Ductal Pancreático / Fator C de Crescimento do Endotélio Vascular / Fator de Transcrição RelA Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Anticancer Res Ano de publicação: 2014 Tipo de documento: Article

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