Clinical features and treatment outcomes of 41 dogs with sublingual ectopic thyroid neoplasia.
J Vet Intern Med
; 28(5): 1560-8, 2014.
Article
em En
| MEDLINE
| ID: mdl-25056508
ABSTRACT
BACKGROUND:
Thyroid neoplasia is common in dogs, but there are few reports of dogs with ectopic, sublingual thyroid tumors.OBJECTIVES:
To describe clinical features and outcomes of dogs with ectopic, sublingual thyroid neoplasia. ANIMALS Five hundred and forty-four dogs with thyroid neoplasia.METHODS:
This retrospective study reviewed the medical records of dogs referred for thyroid neoplasia between 1995 and 2013. Data extracted included signalment, extent of thyroid disease (eutopic or ectopic; metastasis), serum thyroxine (T4) concentration, treatment, and survival.RESULTS:
Of 544 dogs with thyroid neoplasia, 41 (7.5%) dogs had ectopic sublingual thyroid tumors. The clinical features of these 41 dogs were similar to the cohort group of 503 dogs with eutopic or ectopic mediastinal thyroid tumors, but dogs with sublingual tumors were younger and less likely to have metastatic disease (15% versus 30%, P < .05). Of the 41 dogs, 28 received treatment 21 with surgery (which included partial hyoidectomy in 13), 7 with radioiodine alone, and 13 with surgery followed by administration of radioiodine. Overall median survival was 562 days (range, 1-1,850 days). CONCLUSIONS AND CLINICAL IMPORTANCE When compared with eutopic thyroid carcinomas, ectopic sublingual thyroid tumors generally have a less aggressive biologic behavior. Many dogs have prolonged survival, even without treatment, although death because of local tumor invasiveness or metastasis can develop in some dogs. Surgical thyroidectomy, including partial hyoidectomy, is generally effective for control of local disease. Administration of radioiodine, alone or in combination with surgical treatment, is recommended for multifocal disease or metastasis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
/
Doenças do Cão
/
Disgenesia da Tireoide
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
J Vet Intern Med
Ano de publicação:
2014
Tipo de documento:
Article