Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.

Lin, Feng-Yen; Hsiao, Fung-Ping; Huang, Chun-Yao; Shih, Chun-Ming; Tsao, Nai-Wen; Tsai, Chien-Sung; Yang, Shue-Fen; Chang, Nen-Chung; Hung, Shan-Ling; Lin, Yi-Wen

Lin, Feng-Yen; Hsiao, Fung-Ping; Huang, Chun-Yao; Shih, Chun-Ming; Tsao, Nai-Wen; Tsai, Chien-Sung; Yang, Shue-Fen; Chang, Nen-Chung; Hung, Shan-Ling; Lin, Yi-Wen.

Afiliação

Lin FY; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hsiao FP; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan.
Huang CY; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Shih CM; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Tsao NW; Division of Cardiovascular Surgery, Taipei Medical University Hospital, Taipei, Taiwan.
Tsai CS; Division of Cardiovascular Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Yang SF; Department of Dentistry, National Yang-Ming University, Taipei, Taiwan; Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chang NC; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hung SL; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan; Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Lin YW; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan.

PLoS One ; 9(7): e102450, 2014.

Article em En | MEDLINE | ID: mdl-25058444

Assuntos

Perda do Osso Alveolar/microbiologia; Proteínas de Bactérias/genética; Chaperonina 60/genética; Osteoclastos/patologia; Ligamento Periodontal/microbiologia; Periodontite/microbiologia; Perda do Osso Alveolar/genética; Perda do Osso Alveolar/metabolismo; Perda do Osso Alveolar/patologia; Animais; Proteínas de Bactérias/metabolismo; Proteínas de Bactérias/farmacologia; Chaperonina 60/metabolismo; Chaperonina 60/farmacologia; Regulação da Expressão Gênica; Interações Hospedeiro-Patógeno; Humanos; Integrina alfa1/genética; Integrina alfa1/metabolismo; Integrina alfa2/genética; Integrina alfa2/metabolismo; Interleucina-6/biossíntese; Interleucina-6/metabolismo; Interleucina-8/biossíntese; Interleucina-8/metabolismo; Masculino; NF-kappa B/genética; NF-kappa B/metabolismo; Osteoclastos/efeitos dos fármacos; Osteoclastos/metabolismo; Ligamento Periodontal/patologia; Periodontite/genética; Periodontite/metabolismo; Periodontite/patologia; Porphyromonas gingivalis/genética; Porphyromonas gingivalis/metabolismo; Porphyromonas gingivalis/patogenicidade; Ligante RANK/genética; Ligante RANK/metabolismo; Ratos; Ratos Sprague-Dawley; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Proteínas Recombinantes/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoclastos / Ligamento Periodontal / Periodontite / Proteínas de Bactérias / Perda do Osso Alveolar / Chaperonina 60 Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article

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