PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells.
Mol Metab
; 3(5): 518-30, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-25061557
Beta cells; CV, Coxsackievirus; Diabetes; ER, endoplasmic reticulum; EV, Enterovirus; F, Faulkner; FL, firefly luciferase; IRES, internal ribosomal entry site; ITAF, IRES-trans-acting factor; Insulin; MCA, MIN6 cell adapted; PABP, poly(A)-binding protein; PC, prohormone convertase; PTBP1, polypyrimidine tract-binding protein 1; Polypyrimidine tract-binding protein; S6K1, p70S6 Kinase 1; Secretory granules; T1D, type 1 diabetes; Translation; UTR, untranslated region; Virus; eIF4E-V5, eIF4E tagged at its C-terminus with a V5-epitope; mTORC1, mammalian Target Of Rapamycin Complex 1
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Mol Metab
Ano de publicação:
2014
Tipo de documento:
Article