Apoptosis of antigen-specific CTLs contributes to low immune response in gut-associated lymphoid tissue post vaccination.

Shimada, Masaru; Yoshizaki, Shinji; Ichino, Motohide; Klinman, Dennis M; Okuda, Kenji

Shimada, Masaru; Yoshizaki, Shinji; Ichino, Motohide; Klinman, Dennis M; Okuda, Kenji.

Afiliação

Shimada M; Department of Molecular Biodefense Research, Yokohama City University, Graduate School of Medicine, Yokohama 236-0004, Japan. Electronic address: mshimada@yokohama-cu.ac.jp.
Yoshizaki S; Department of Molecular Biodefense Research, Yokohama City University, Graduate School of Medicine, Yokohama 236-0004, Japan.
Ichino M; Department of Immunology, Yokohama City University, Graduate School of Medicine, Yokohama 236-0004, Japan.
Klinman DM; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, United States.
Okuda K; Department of Molecular Biodefense Research, Yokohama City University, Graduate School of Medicine, Yokohama 236-0004, Japan.

Vaccine ; 32(40): 5198-205, 2014 Sep 08.

Article em En | MEDLINE | ID: mdl-25066739

Assuntos

Apoptose/imunologia; Infecções por HIV/imunologia; Mucosa Intestinal/imunologia; Tecido Linfoide/imunologia; Linfócitos T Citotóxicos/imunologia; Animais; Linfócitos T CD8-Positivos/imunologia; Feminino; Camundongos; Camundongos Endogâmicos BALB C; Receptor de Morte Celular Programada 1/metabolismo

Palavras-chave

Mouse; Programmed cell death protein-1 (PD-1); Vaccine; Virus vector

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / Infecções por HIV / Apoptose / Mucosa Intestinal / Tecido Linfoide Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Vaccine Ano de publicação: 2014 Tipo de documento: Article

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