Conformational analysis of the Streptococcus pneumoniae hyaluronate lyase and characterization of its hyaluronan-specific carbohydrate-binding module.

Suits, Michael D L; Pluvinage, Benjamin; Law, Adrienne; Liu, Yan; Palma, Angelina S; Chai, Wengang; Feizi, Ten; Boraston, Alisdair B

Suits, Michael D L; Pluvinage, Benjamin; Law, Adrienne; Liu, Yan; Palma, Angelina S; Chai, Wengang; Feizi, Ten; Boraston, Alisdair B.

Afiliação

Suits MDL; Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada.
Pluvinage B; Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada.
Law A; Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada.
Liu Y; Glycosciences Laboratory, Imperial College London, Burlington Danes Building, Du Cane Road, London W12 0NN, United Kingdom, and.
Palma AS; Glycosciences Laboratory, Imperial College London, Burlington Danes Building, Du Cane Road, London W12 0NN, United Kingdom, and; REQUIMTE, Department of Chemistry, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
Chai W; Glycosciences Laboratory, Imperial College London, Burlington Danes Building, Du Cane Road, London W12 0NN, United Kingdom, and.
Feizi T; Glycosciences Laboratory, Imperial College London, Burlington Danes Building, Du Cane Road, London W12 0NN, United Kingdom, and.
Boraston AB; Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada,. Electronic address: boraston@uvic.ca.

J Biol Chem ; 289(39): 27264-27277, 2014 Sep 26.

Article em En | MEDLINE | ID: mdl-25100731

Assuntos

Proteínas de Bactérias/química; Polissacarídeo-Liases/química; Multimerização Proteica; Streptococcus pneumoniae/enzimologia; Proteínas de Bactérias/genética; Cristalografia por Raios X; Mutagênese Sítio-Dirigida; Polissacarídeo-Liases/genética; Estrutura Quaternária de Proteína; Estrutura Terciária de Proteína; Streptococcus pneumoniae/genética

Palavras-chave

Carbohydrate; Carbohydrate Processing; Carbohydrate-binding Protein; Crystallography; Glycobiology; Hyaluronan; Hyaluronate Lyase; Small Angle X-ray Scattering (SAXS); Streptococcus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeo-Liases / Streptococcus pneumoniae / Proteínas de Bactérias / Multimerização Proteica Idioma: En Revista: J Biol Chem Ano de publicação: 2014 Tipo de documento: Article

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