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α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction.
Jin, Yi; Bhattasali, Debabrata; Pellegrini, Erika; Forget, Stephanie M; Baxter, Nicola J; Cliff, Matthew J; Bowler, Matthew W; Jakeman, David L; Blackburn, G Michael; Waltho, Jonathan P.
Afiliação
  • Jin Y; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom;
  • Bhattasali D; Department of Chemistry, College of Pharmacy, Dalhousie University, Halifax, NS, Canada B3H 4R2;
  • Pellegrini E; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom; Structural Biology Group, European Synchrotron Radiation Facility, 38042 Grenoble, Cedex 9, France; European Molecular Biology Laboratory, Grenoble Outstation
  • Forget SM; Department of Chemistry, College of Pharmacy, Dalhousie University, Halifax, NS, Canada B3H 4R2;
  • Baxter NJ; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom;
  • Cliff MJ; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom; Manchester Institute of Biotechnology, Manchester M1 7DN, United Kingdom; and.
  • Bowler MW; Structural Biology Group, European Synchrotron Radiation Facility, 38042 Grenoble, Cedex 9, France; European Molecular Biology Laboratory, Grenoble Outstation, 38042 Grenoble, Cedex 9, France; Unit of Virus Host Cell Interactions, University of Grenoble Alpes-European Molecular Biology Laboratory-Ce
  • Jakeman DL; Department of Chemistry, College of Pharmacy, Dalhousie University, Halifax, NS, Canada B3H 4R2; david.jakeman@dal.ca g.m.blackburn@sheffield.ac.uk j.waltho@sheffield.ac.uk.
  • Blackburn GM; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom; david.jakeman@dal.ca g.m.blackburn@sheffield.ac.uk j.waltho@sheffield.ac.uk.
  • Waltho JP; Department of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom; Manchester Institute of Biotechnology, Manchester M1 7DN, United Kingdom; and david.jakeman@dal.ca g.m.blackburn@sheffield.ac.uk j.waltho@sheffield.ac.uk.
Proc Natl Acad Sci U S A ; 111(34): 12384-9, 2014 Aug 26.
Article em En | MEDLINE | ID: mdl-25104750
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoglucomutase / Organofosfonatos / Hexoses Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoglucomutase / Organofosfonatos / Hexoses Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article