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The p38 MAPK-regulated PKD1/CREB/Bcl-2 pathway contributes to selenite-induced colorectal cancer cell apoptosis in vitro and in vivo.
Hui, Kaiyan; Yang, Yang; Shi, Kejian; Luo, Hui; Duan, Jing; An, Jiajia; Wu, Pa; Ci, Yali; Shi, Lei; Xu, Caimin.
Afiliação
  • Hui K; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Yang Y; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Shi K; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Luo H; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Duan J; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • An J; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Wu P; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Ci Y; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Shi L; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China.
  • Xu C; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, NO. 5 Dong Dan San Tiao, Beijing 100005, China. Electronic address: cmxu@ibms.pumc.edu.cn.
Cancer Lett ; 354(1): 189-99, 2014 Nov 01.
Article em En | MEDLINE | ID: mdl-25128071
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico / Apoptose / Ácido Selenioso / Proteínas Quinases p38 Ativadas por Mitógeno / Canais de Cátion TRPP Limite: Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico / Apoptose / Ácido Selenioso / Proteínas Quinases p38 Ativadas por Mitógeno / Canais de Cátion TRPP Limite: Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2014 Tipo de documento: Article