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Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New Guinea.
Barnadas, Celine; Senn, Nicolas; Iga, Jonah; Timinao, Lincoln; Javati, Sarah; Malau, Elisheba; Rarau, Patricia; Reeder, John C; Siba, Peter; Karunajeewa, Harin; Zimmerman, Peter A; Davis, Timothy M; Mueller, Ivo.
Afiliação
  • Barnadas C; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea Infection and Immunity Division, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia Department of Medical Biology, University of Melbourne, Parkville, Australia barn
  • Senn N; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Iga J; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea.
  • Timinao L; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea.
  • Javati S; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea.
  • Malau E; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea Infection and Immunity Division, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia.
  • Rarau P; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea.
  • Reeder JC; Burnet Institute, Melbourne, Australia.
  • Siba P; Vector Borne Diseases Unit, Papua New Guinea Institute of Medical Research (PNGIMR), Goroka, Papua New Guinea.
  • Karunajeewa H; Infection and Immunity Division, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia Department of Medical Biology, University of Melbourne, Parkville, Australia.
  • Zimmerman PA; Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio, USA.
  • Davis TM; School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.
  • Mueller I; Infection and Immunity Division, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia Department of Medical Biology, University of Melbourne, Parkville, Australia Centre de Recerca en Salut Internacional de Barcelona, Barcelona, Spain barnadas@wehi.edu.au ivomueller@fastmail.f
Antimicrob Agents Chemother ; 58(11): 6958-61, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25155586
ABSTRACT
Intermittent preventive treatment of infants (IPTi) reduces early childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial drugs in case management, there are few equivalent data relating to their protective efficacy when used as IPTi. The present data from an IPTi trial in Papua New Guinea demonstrate how these markers can predict protective efficacy of IPTi for both Plasmodium falciparum and Plasmodium vivax.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Plasmodium vivax / Resistência a Medicamentos / Antimaláricos Limite: Humans / Infant Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Plasmodium vivax / Resistência a Medicamentos / Antimaláricos Limite: Humans / Infant Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2014 Tipo de documento: Article