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Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Rankin, Erinn B; Fuh, Katherine C; Castellini, Laura; Viswanathan, Kartik; Finger, Elizabeth C; Diep, Anh N; LaGory, Edward L; Kariolis, Mihalis S; Chan, Andy; Lindgren, David; Axelson, Håkan; Miao, Yu R; Krieg, Adam J; Giaccia, Amato J.
Afiliação
  • Rankin EB; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Fuh KC; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Castellini L; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Viswanathan K; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Finger EC; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Diep AN; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • LaGory EL; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Kariolis MS; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Chan A; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Lindgren D; Department of Laboratory Medicine, Center for Molecular Pathology, Lund University, Skåne University Hospital, SE-205 02 Malmö, Sweden; and.
  • Axelson H; Department of Laboratory Medicine, Center for Molecular Pathology, Lund University, Skåne University Hospital, SE-205 02 Malmö, Sweden; and.
  • Miao YR; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;
  • Krieg AJ; Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS 66160.
  • Giaccia AJ; Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305; giaccia@stanford.edu.
Proc Natl Acad Sci U S A ; 111(37): 13373-8, 2014 Sep 16.
Article em En | MEDLINE | ID: mdl-25187556
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Receptores Proteína Tirosina Quinases / Quinases da Família src / Proteínas Proto-Oncogênicas c-met / Peptídeos e Proteínas de Sinalização Intercelular / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Receptores Proteína Tirosina Quinases / Quinases da Família src / Proteínas Proto-Oncogênicas c-met / Peptídeos e Proteínas de Sinalização Intercelular / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article