Involvement of tumor macrophage HIFs in chemotherapy effectiveness: mathematical modeling of oxygen, pH, and glutathione.

Chen, Duan; Bobko, Andrey A; Gross, Amy C; Evans, Randall; Marsh, Clay B; Khramtsov, Valery V; Eubank, Timothy D; Friedman, Avner

Chen, Duan; Bobko, Andrey A; Gross, Amy C; Evans, Randall; Marsh, Clay B; Khramtsov, Valery V; Eubank, Timothy D; Friedman, Avner.

Afiliação

Chen D; Department of Mathematics and Statistics, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America.
Bobko AA; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Gross AC; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Evans R; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Marsh CB; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Khramtsov VV; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Eubank TD; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Friedman A; Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America; Department of Mathematics, The Ohio State University, Columbus, Ohio, United States of America.

PLoS One ; 9(10): e107511, 2014.

Article em En | MEDLINE | ID: mdl-25295611

Assuntos

Fatores de Transcrição Hélice-Alça-Hélice Básicos/metabolismo; Neoplasias da Mama/metabolismo; Glutationa/metabolismo; Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo; Macrófagos/metabolismo; Modelos Teóricos; Oxigênio/metabolismo; Animais; Feminino; Concentração de Íons de Hidrogênio; Camundongos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Neoplasias da Mama / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Glutationa / Macrófagos / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article

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