[Taufon use in myopic contact lens wearers].
Vestn Oftalmol
; 130(4): 97-8, 100-1, 2014.
Article
em Ru
| MEDLINE
| ID: mdl-25306731
ABSTRACT
PURPOSE:
To investigate the potential clinical efficacy of Taufon eye drops in silicone hydrogel soft contact lens wearers with nonprogressive myopia. MATERIAL ANDMETHODS:
A total of 90 patients with non-progressive myopia aged from 28 to 45 years were divided in 3 homogeneous groups (30 patients in each). For vision correction silicone hydrogel Air Optix Night & Day ("Ciba Vision") and Pure Vision 2HD ("Bausch & Lomb") contact lenses were used. The average period of contact lens wear was 5.5 +/- 3.3 years. Apart from conventional ophthalmic assessment, all patients underwent a complex lacrimal system examination, which included Schirmer's test and tear film break-up time (TBUT). The Ocular Surface Disease Index (OSDI) was used for dry eye symptoms assessment. The condition of the corneal epithelium was evaluated after 0.2% fluorescein instillation. Group 1 patients received 4% Taufon eye drops, group 2--natural tears ("Alcon"). Group 3 patients did not use any eye drops at all.RESULTS:
Baseline Schirmer's test results, TBUT, and OSDI score were similar in all groups (p < 0.05, Mann-Whitney test). Drug therapy was considered effective if Schirmer's test result remained > 10 mm, TBUT--not less than 10 sec, OSDI--not more than 15, there were positive dynamics or at least no negative changes in dry eye signs and symptoms. The patients from group 1 presented no subjective complaits and their corneal and conjunctival changes were less significant than that in other groups (p < 0.05). Regression of dry eye signs at biomicroscopy in this group was confirmed by Schirmer's test results, TBUT, and OSDI. In groups 2 and 3 dry eye sings were more pronounced.CONCLUSION:
The study of the 4% Taufon eye drops efficacy for dry eye prevention in silicone hydrogel Air Optix Night & Day and Pure Vision 2HD contact lens wearers with non-progressive myopia showed that the clinical effect was more significant in the treatment group (group 1) as compared to both group 2 (natural tear) and 3 (p < 0.05).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Taurina
/
Síndromes do Olho Seco
/
Lentes de Contato Hidrofílicas
/
Miopia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
/
Europa
Idioma:
Ru
Revista:
Vestn Oftalmol
Ano de publicação:
2014
Tipo de documento:
Article