[Effect of nasal instillation of vitamin D3 on patient with allergic rhinitis symptoms].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
; 28(14): 1031-3, 2014 Jul.
Article
em Zh
| MEDLINE
| ID: mdl-25330636
ABSTRACT
OBJECTIVE:
To investigate the effect of nasal instillation of vitamin D3 on patients with allergic rhinitis symptoms including nasal itching, sneezing, clear nasal discharge, and nasal congestion.METHOD:
Thirty subjects with allergic rhinitis proved by skin prick test (SPT) and 30 subjects with deviated septum alone were recrui ted and administrated with 300 000 IU of vitamin D3 by nasal instillation weekly. Seven days after the intervention, the four major symptoms including nasal itching, sneezing, clear nasal discharge, and nasal congestion were evaluated by score.RESULT:
After intranasal instillation of vitamin D3, the symptoms in allergic rhinitis group in cluding nasal itching, sneezing, nasal discharge and nasal congestion, and serum 25-hydroxyvitamin D level has statistical differences (P < 0.05).CONCLUSION:
Vitamin D3 could be well absorbed through nasal mucosa. It demonstrated to have significantly effect on serum 25-hydroxyvitamin D to improve the symptoms for patients with allergic rhinitis. Vitamin D3 may be a kind of adjuvant therapy for prevention and treatment of allergic rhinitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Colecalciferol
/
Rinite Alérgica
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Ano de publicação:
2014
Tipo de documento:
Article