The emerging link between O-GlcNAc and Alzheimer disease.

Zhu, Yanping; Shan, Xiaoyang; Yuzwa, Scott A; Vocadlo, David J

Zhu, Yanping; Shan, Xiaoyang; Yuzwa, Scott A; Vocadlo, David J.

Afiliação

Zhu Y; From the Departments of Molecular Biology and Biochemistry and Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
Shan X; From the Departments of Molecular Biology and Biochemistry and.
Yuzwa SA; From the Departments of Molecular Biology and Biochemistry and.
Vocadlo DJ; From the Departments of Molecular Biology and Biochemistry and Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada dvocadlo@sfu.ca.

J Biol Chem ; 289(50): 34472-81, 2014 Dec 12.

Article em En | MEDLINE | ID: mdl-25336656

Assuntos

Acetilglucosamina/metabolismo; Doença de Alzheimer/metabolismo; Doença de Alzheimer/etiologia; Doença de Alzheimer/patologia; Peptídeos beta-Amiloides/metabolismo; Animais; Glucose/metabolismo; Humanos; Neurônios/metabolismo; Proteínas tau/metabolismo

Palavras-chave

Alzheimer Disease; Amyloid-ß (Aß); Brain Metabolism; Glucose Metabolism; Glycobiology; Glycoprotein; Glycosylation; O-GlcNAcylation; O-Linked N-Acetylglucosamine (O-GlcNAc); Tau Protein (Tau)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilglucosamina / Doença de Alzheimer Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2014 Tipo de documento: Article

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