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Cantharidin induces G2/M phase arrest by inhibition of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria­dependent pathways of A375.S2 human melanoma cells.
Hsiao, Yu-Ping; Tsai, Chung-Hung; Wu, Ping-Ping; Hsu, Shu-Chun; Liu, Hsin-Chung; Huang, Yi-Ping; Yang, Jen-Hung; Chung, Jing-Gung.
Afiliação
  • Hsiao YP; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
  • Tsai CH; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
  • Wu PP; School of Pharmacy, China Medical University, Taichung, Taiwan, R.O.C.
  • Hsu SC; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
  • Liu HC; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
  • Huang YP; Department of Physiology, China Medical University, Taichung, Taiwan, R.O.C.
  • Yang JH; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, R.O.C.
  • Chung JG; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Int J Oncol ; 45(6): 2393-402, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25340978
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Cantaridina / Ciclina A / Fosfatases cdc25 / Melanoma Limite: Humans Idioma: En Revista: Int J Oncol Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Cantaridina / Ciclina A / Fosfatases cdc25 / Melanoma Limite: Humans Idioma: En Revista: Int J Oncol Ano de publicação: 2014 Tipo de documento: Article