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DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
Kim, Younghee; Tarallo, Valeria; Kerur, Nagaraj; Yasuma, Tetsuhiro; Gelfand, Bradley D; Bastos-Carvalho, Ana; Hirano, Yoshio; Yasuma, Reo; Mizutani, Takeshi; Fowler, Benjamin J; Li, Shengjian; Kaneko, Hiroki; Bogdanovich, Sasha; Ambati, Balamurali K; Hinton, David R; Hauswirth, William W; Hakem, Razqallah; Wright, Charles; Ambati, Jayakrishna.
Afiliação
  • Kim Y; Department of Ophthalmology and Visual Sciences.
  • Tarallo V; Department of Ophthalmology and Visual Sciences, Angiogenesis Lab, Institute of Genetics and Biophysics, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy;
  • Kerur N; Department of Ophthalmology and Visual Sciences.
  • Yasuma T; Department of Ophthalmology and Visual Sciences.
  • Gelfand BD; Department of Ophthalmology and Visual Sciences, Department of Biomedical Engineering, Department of Microbiology, Immunology, and Human Genetics, and.
  • Bastos-Carvalho A; Department of Ophthalmology and Visual Sciences.
  • Hirano Y; Department of Ophthalmology and Visual Sciences.
  • Yasuma R; Department of Ophthalmology and Visual Sciences.
  • Mizutani T; Department of Ophthalmology and Visual Sciences.
  • Fowler BJ; Department of Ophthalmology and Visual Sciences, Department of Physiology, University of Kentucky, Lexington, KY 40536;
  • Li S; Department of Ophthalmology and Visual Sciences.
  • Kaneko H; Department of Ophthalmology and Visual Sciences.
  • Bogdanovich S; Department of Ophthalmology and Visual Sciences.
  • Ambati BK; Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT 84132; Department of Ophthalmology, Veterans Affairs Salt Lake City Healthcare System, Salt Lake City, UT 84148;
  • Hinton DR; Departments of Pathology and Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033;
  • Hauswirth WW; Department of Ophthalmology, University of Florida, Gainesville, FL 32610; and.
  • Hakem R; Ontario Cancer Institute, University Health Network, and Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada M5G 2M9.
  • Wright C; Department of Ophthalmology and Visual Sciences.
  • Ambati J; Department of Ophthalmology and Visual Sciences, Department of Physiology, University of Kentucky, Lexington, KY 40536; jamba2@email.uky.edu.
Proc Natl Acad Sci U S A ; 111(45): 16082-7, 2014 Nov 11.
Article em En | MEDLINE | ID: mdl-25349431

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Apoptose / Elementos Alu / Ribonuclease III / Caspase 8 / RNA Helicases DEAD-box / Proteínas do Olho / Degeneração Macular Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Apoptose / Elementos Alu / Ribonuclease III / Caspase 8 / RNA Helicases DEAD-box / Proteínas do Olho / Degeneração Macular Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article