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(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.
Mahmoud, Mariam M; Olszewska, Teresa; Liu, Hui; Shore, Derek M; Hurst, Dow P; Reggio, Patricia H; Lu, Dai; Kendall, Debra A.
Afiliação
  • Mahmoud MM; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Olszewska T; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Liu H; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Shore DM; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Hurst DP; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Reggio PH; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Lu D; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
  • Kendall DA; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut (M.M.M.); Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas (T.O., H. L., D.L.); Department of Chemistry and Biochemistry, University of North Carolina at Greensboro,
Mol Pharmacol ; 87(2): 197-206, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25411367
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Compostos Benzidrílicos / Canabinoides / Receptor CB1 de Canabinoide / Agonismo Inverso de Drogas Limite: Animals / Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Compostos Benzidrílicos / Canabinoides / Receptor CB1 de Canabinoide / Agonismo Inverso de Drogas Limite: Animals / Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2015 Tipo de documento: Article