Targeted Screening and Quantification of dl-PCBs and Dioxins in Various Foodstuffs by Programmed-temperature Vaporizer Large-volume Injection Coupled to GC-MS.
Chimia (Aarau)
; 68(10): 732-8, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-25437167
ABSTRACT
In 2009, high concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dl-PCBs) were found in soils located near the municipal garbage incinerator of Geneva. The matter of food contamination in this area was raised. Based on exposure criteria, a strategy of analysis of animal fats has been established with farmers in the Geneva area. Most methods of analysis of dl-PCBs, dioxins and furans, are based on gas chromatography coupled to high-resolution mass spectrometry (GC-HRMS) and considered as the reference methodology. An innovative approach was developed by programmed-temperature vaporizer large-volume injection (PTV-LV) and gas chromatography coupled with triple quadrupole mass spectrometry (GC-MS/MS) analysis. This analytical method was validated and was found suitable for screening and quantification of target compounds in animal fats (beef, pork, sheep, etc. ). PTV-LV coupled to GC-MS/MS appeared to be a good alternative compared to the GC-HRMS strategy, offering a good compromise between sensitivity, versatility of instrumentation, and economical aspects. A survey of 121 samples was conducted.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Contaminação de Alimentos
/
Dioxinas
/
Cromatografia Gasosa-Espectrometria de Massas
/
Carne
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Animals
Idioma:
En
Revista:
Chimia (Aarau)
Ano de publicação:
2014
Tipo de documento:
Article