Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture.

Johar, Angad S; Anaya, Juan-Manuel; Andrews, Dan; Patel, Hardip R; Field, Matthew; Goodnow, Chris; Arcos-Burgos, Mauricio

Johar, Angad S; Anaya, Juan-Manuel; Andrews, Dan; Patel, Hardip R; Field, Matthew; Goodnow, Chris; Arcos-Burgos, Mauricio.

Afiliação

Johar AS; Genomics and Predictive Medicine, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT, Australia.
Anaya JM; Centre for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia. Electronic address: juan.anaya@urosario.edu.co.
Andrews D; Immunogenomics and Bioinformatics Group, Immunology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT, Australia.
Patel HR; Genome Discovery Unit, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT, Australia.
Field M; Immunogenomics and Bioinformatics Group, Immunology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT, Australia.
Goodnow C; Immunogenomics and Bioinformatics Group, Immunology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT, Australia.
Arcos-Burgos M; Genomics and Predictive Medicine, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT, Australia. Electronic address: Mauricio.Arcos-Burgos@anu.edu.au.

Autoimmun Rev ; 14(3): 204-9, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25447288

Assuntos

Autoimunidade; Exoma; Genômica; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Fenótipo; Análise de Sequência de DNA

Palavras-chave

Multiple autoimmune syndrome; Next generation sequencing; Polyautoimmunity; Whole exome sequencing; Whole genome sequencing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoimunidade Limite: Humans Idioma: En Revista: Autoimmun Rev Ano de publicação: 2015 Tipo de documento: Article

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