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CFS-1686 causes cell cycle arrest at intra-S phase by interference of interaction of topoisomerase 1 with DNA.
Lin, Ru-Wei; Yang, Chia-Ning; Ku, ShengYu; Ho, Cheng-Jung; Huang, Shih-Bo; Yang, Min-Chi; Chang, Hsin-Wen; Lin, Chun-Mao; Hwang, Jaulang; Chen, Yeh-Long; Tzeng, Cherg-Chyi; Wang, Chihuei.
Afiliação
  • Lin RW; Bone and Joint Research Center, National Cheng Kung University, Tainan, Taiwan; Medical Device R & D Core Laboratory, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan.
  • Yang CN; Department of Life Sciences, National University of Kaohsiung, Kaohsiung, Taiwan.
  • Ku S; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Ho CJ; Department of Orthopedics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
  • Huang SB; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Yang MC; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Chang HW; Department of Life Sciences, National University of Kaohsiung, Kaohsiung, Taiwan.
  • Lin CM; Department of Biochemistry, School of Medical, Taipei Medical University, Taipei, Taiwan.
  • Hwang J; Department of Biochemistry, School of Medical, Taipei Medical University, Taipei, Taiwan.
  • Chen YL; Department of Medical and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Tzeng CC; Department of Medical and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Wang C; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan.
PLoS One ; 9(12): e113832, 2014.
Article em En | MEDLINE | ID: mdl-25460368
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / DNA de Neoplasias / Fase S / DNA Topoisomerases Tipo I / Pontos de Checagem do Ciclo Celular / Aminoquinolinas Tipo de estudo: Etiology_studies Limite: Humans / Male Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / DNA de Neoplasias / Fase S / DNA Topoisomerases Tipo I / Pontos de Checagem do Ciclo Celular / Aminoquinolinas Tipo de estudo: Etiology_studies Limite: Humans / Male Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article