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The SAR development of substituted purine derivatives as selective CB2 agonists for the treatment of chronic pain.
Guidetti, Rossella; Astles, Peter C; Sanderson, Adam J; Hollinshead, Sean P; Johnson, Michael P; Chambers, Mark G.
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  • Guidetti R; Discovery Chemistry, Erl Wood Manor, Lilly Research Laboratories, A Division of Eli Lilly and Company, Sunningdale Road, Windlesham, Surrey GU20 6PH, UK. Electronic address: guidetti_rossella_rg@lilly.com.
  • Astles PC; Discovery Chemistry, Erl Wood Manor, Lilly Research Laboratories, A Division of Eli Lilly and Company, Sunningdale Road, Windlesham, Surrey GU20 6PH, UK.
  • Sanderson AJ; Discovery Chemistry, Erl Wood Manor, Lilly Research Laboratories, A Division of Eli Lilly and Company, Sunningdale Road, Windlesham, Surrey GU20 6PH, UK.
  • Hollinshead SP; Discovery Chemistry, Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA.
  • Johnson MP; Neuroscience Discovery, Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA.
  • Chambers MG; Musculoskeletal Research, Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA.
Bioorg Med Chem Lett ; 24(24): 5572-5575, 2014 Dec 15.
Article em En | MEDLINE | ID: mdl-25466177
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Purinas / Receptor CB2 de Canabinoide / Dor Crônica / Agonistas de Receptores de Canabinoides Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Purinas / Receptor CB2 de Canabinoide / Dor Crônica / Agonistas de Receptores de Canabinoides Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2014 Tipo de documento: Article