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A phase I study of oral ARRY-614, a p38 MAPK/Tie2 dual inhibitor, in patients with low or intermediate-1 risk myelodysplastic syndromes.
Garcia-Manero, Guillermo; Khoury, Hanna J; Jabbour, Elias; Lancet, Jeffrey; Winski, Shannon L; Cable, LouAnn; Rush, Selena; Maloney, Lara; Hogeland, Grant; Ptaszynski, Mieke; Calvo, Monica Cabrero; Bohannan, Zach; List, Alan; Kantarjian, Hagop; Komrokji, Rami.
Afiliação
  • Garcia-Manero G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas. ggarciam@mdanderson.org.
  • Khoury HJ; Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Jabbour E; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Lancet J; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
  • Winski SL; Array BioPharma Inc., Boulder, Colorado.
  • Cable L; Array BioPharma Inc., Boulder, Colorado.
  • Rush S; Array BioPharma Inc., Boulder, Colorado.
  • Maloney L; Array BioPharma Inc., Boulder, Colorado.
  • Hogeland G; Array BioPharma Inc., Boulder, Colorado.
  • Ptaszynski M; Array BioPharma Inc., Boulder, Colorado.
  • Calvo MC; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Bohannan Z; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • List A; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
  • Kantarjian H; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Komrokji R; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Clin Cancer Res ; 21(5): 985-94, 2015 Mar 01.
Article em En | MEDLINE | ID: mdl-25480830
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Ureia / Síndromes Mielodisplásicas / Receptor TIE-2 / Proteínas Quinases p38 Ativadas por Mitógeno / Inibidores de Proteínas Quinases / Indazóis / Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Ureia / Síndromes Mielodisplásicas / Receptor TIE-2 / Proteínas Quinases p38 Ativadas por Mitógeno / Inibidores de Proteínas Quinases / Indazóis / Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Ano de publicação: 2015 Tipo de documento: Article