Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.

Askmyr, M; Ågerstam, H; Lilljebjörn, H; Hansen, N; Karlsson, C; von Palffy, S; Landberg, N; Högberg, C; Lassen, C; Rissler, M; Richter, J; Ehinger, M; Järås, M; Fioretos, T

Askmyr, M; Ågerstam, H; Lilljebjörn, H; Hansen, N; Karlsson, C; von Palffy, S; Landberg, N; Högberg, C; Lassen, C; Rissler, M; Richter, J; Ehinger, M; Järås, M; Fioretos, T.

Afiliação

Askmyr M; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Ågerstam H; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Lilljebjörn H; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Hansen N; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Karlsson C; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
von Palffy S; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Landberg N; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Högberg C; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Lassen C; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Rissler M; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Richter J; Department of Molecular Medicine and Gene Therapy, Lund University and Department of Hematology and Vascular Disorders, Skåne University Hospital, Lund, Sweden.
Ehinger M; Department of Pathology, University and Regional Laboratories, Skåne University Hospital, Lund University, Lund, Sweden.
Järås M; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.
Fioretos T; Department of Clinical Genetics, University and Regional Laboratories, Lund University Hospital, Lund University, Lund, Sweden.

Blood Cancer J ; 4: e269, 2014 Dec 12.

Article em En | MEDLINE | ID: mdl-25501026

Assuntos

Proliferação de Células; Transformação Celular Neoplásica/metabolismo; Leucemia Mielogênica Crônica BCR-ABL Positiva/metabolismo; Mastócitos/metabolismo; Neoplasias Experimentais/metabolismo; Células Precursoras de Linfócitos B/metabolismo; Animais; Transformação Celular Neoplásica/genética; Transformação Celular Neoplásica/patologia; Sangue Fetal/metabolismo; Proteínas de Fusão bcr-abl/biossíntese; Proteínas de Fusão bcr-abl/genética; Xenoenxertos; Humanos; Leucemia Mielogênica Crônica BCR-ABL Positiva/genética; Leucemia Mielogênica Crônica BCR-ABL Positiva/patologia; Mastócitos/patologia; Camundongos; Camundongos Endogâmicos NOD; Camundongos Knockout; Camundongos SCID; Transplante de Neoplasias; Neoplasias Experimentais/genética; Neoplasias Experimentais/patologia; Células Precursoras de Linfócitos B/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Transformação Celular Neoplásica / Proliferação de Células / Células Precursoras de Linfócitos B / Mastócitos / Neoplasias Experimentais Limite: Animals / Humans Idioma: En Revista: Blood Cancer J Ano de publicação: 2014 Tipo de documento: Article

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