Bilateral thalamic stimulation induces insomnia in patients treated for intractable tremor.
Sleep
; 38(3): 473-8, 2015 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-25515098
ABSTRACT
STUDY OBJECTIVES:
To explore the influence of acute bilateral ventral intermediate thalamic nucleus (VIM) stimulation on sleep.DESIGN:
Three consecutive full-night polysomnography recordings were made in the laboratory. After the habituation night, a random order for night ON-stim and OFF-stim was applied for the second and third nights.SETTING:
Sleep disorders unit of a university hospital. PATIENTS Eleven patients with bilateral stimulation of the ventral intermediate nucleus of the thalamus (VIM) for drug-resistant tremor. MEASUREMENTS Sleep measures on polysomnography.RESULTS:
Total sleep time was reduced during night ON-stim compared to OFF- stim, as well as rapid eye movement sleep percentage while the percentage of N2 increased. Wakefulness after sleep onset time was increased.CONCLUSION:
Our results show that bilateral stimulation of the VIM nuclei reduces sleep and could be associated with insomnia.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Núcleos Talâmicos
/
Tremor
/
Distúrbios do Início e da Manutenção do Sono
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Sleep
Ano de publicação:
2015
Tipo de documento:
Article