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The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.
Okada, Tomoyo; Sinha, Surajit; Esposito, Ilaria; Schiavon, Gaia; López-Lago, Miguel A; Su, Wenjing; Pratilas, Christine A; Abele, Cristina; Hernandez, Jonathan M; Ohara, Masahiro; Okada, Morihito; Viale, Agnes; Heguy, Adriana; Socci, Nicholas D; Sapino, Anna; Seshan, Venkatraman E; Long, Stephen; Inghirami, Giorgio; Rosen, Neal; Giancotti, Filippo G.
Afiliação
  • Okada T; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Sinha S; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Esposito I; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Schiavon G; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • López-Lago MA; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Su W; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Pratilas CA; 1] Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Department of Pediatrics, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Abele C; Department of Biomedical Sciences and Human Oncology, Center of Experimental Medicine and Research, University of Torino, Torino 10126, Italy.
  • Hernandez JM; 1] Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Department of Surgery, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Ohara M; Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
  • Okada M; Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
  • Viale A; Genomics Core Facility, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Heguy A; Geoffrey Beene Translational Oncology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Socci ND; Bioinformatics Core Facility, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Sapino A; Department of Medical Sciences, Center of Experimental Medicine and Research, University of Torino, Torino 10126, Italy.
  • Seshan VE; Department of Epidemiology and Biostatistics, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Long S; Structural Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Inghirami G; Department of Biomedical Sciences and Human Oncology, Center of Experimental Medicine and Research, University of Torino, Torino 10126, Italy.
  • Rosen N; 1] Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Department of Medicine, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Giancotti FG; Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
Nat Cell Biol ; 17(1): 81-94, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25531777
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Proteínas rho de Ligação ao GTP / Transição Epitelial-Mesenquimal / Neoplasias de Mama Triplo Negativas / Neoplasias Pulmonares Limite: Animals / Female / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Proteínas rho de Ligação ao GTP / Transição Epitelial-Mesenquimal / Neoplasias de Mama Triplo Negativas / Neoplasias Pulmonares Limite: Animals / Female / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2015 Tipo de documento: Article