Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit.

Isensee, Jörg; Wenzel, Carsten; Buschow, Rene; Weissmann, Robert; Kuss, Andreas W; Hucho, Tim

Isensee, Jörg; Wenzel, Carsten; Buschow, Rene; Weissmann, Robert; Kuss, Andreas W; Hucho, Tim.

Afiliação

Isensee J; Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Cologne, Germany; Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Wenzel C; Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Buschow R; Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Weissmann R; Department of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
Kuss AW; Department of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
Hucho T; Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Cologne, Germany; Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

PLoS One ; 9(12): e115731, 2014.

Article em En | MEDLINE | ID: mdl-25551770

Assuntos

Gânglios Espinais/metabolismo; Nociceptores/metabolismo; Comunicação Parácrina/genética; Prostaglandina D2/metabolismo; Canais de Cátion TRPV/metabolismo; Animais; Sequência de Bases; Capsaicina/farmacologia; Células Cultivadas; Perfilação da Expressão Gênica; Masculino; Dor/genética; Fosfatidilinositóis/metabolismo; Canais de Potássio/metabolismo; Prostaglandina D2/biossíntese; Ratos; Ratos Sprague-Dawley; Receptores Acoplados a Proteínas G/metabolismo; Análise de Sequência de DNA; Canais de Cátion TRPV/agonistas; Canais de Cátion TRPV/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nociceptores / Prostaglandina D2 / Comunicação Parácrina / Canais de Cátion TRPV / Gânglios Espinais Limite: Animals Idioma: En Revista: PLoS One Ano de publicação: 2014 Tipo de documento: Article

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