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Facile syntheses of functionalized toll-like receptor 7 agonists.
Akinbobuyi, Babatope; Byrd, Matthew R; Chang, Charles A; Nguyen, Mysa; Seifert, Zacharie J; Flamar, Anne-Laure; Zurawski, Gerard; Upchurch, Katherine C; Oh, SangKon; Dempsey, Stephen H; Enke, Thomas J; Le, John; Winstead, Hunter J; Boquín, José R; Kane, Robert R.
Afiliação
  • Akinbobuyi B; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA.
  • Byrd MR; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA.
  • Chang CA; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA.
  • Nguyen M; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA.
  • Seifert ZJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA.
  • Flamar AL; Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas, TX 75204, USA.
  • Zurawski G; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA ; Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas, TX 75204, USA.
  • Upchurch KC; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA.
  • Oh S; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA ; Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas, TX 75204, USA.
  • Dempsey SH; Department of Chemistry, Augustana College, 639 38 Street, Rock Island, IL 61201, USA.
  • Enke TJ; Department of Chemistry, Augustana College, 639 38 Street, Rock Island, IL 61201, USA.
  • Le J; Department of Chemistry, Augustana College, 639 38 Street, Rock Island, IL 61201, USA.
  • Winstead HJ; Department of Chemistry, Augustana College, 639 38 Street, Rock Island, IL 61201, USA.
  • Boquín JR; Department of Chemistry, Augustana College, 639 38 Street, Rock Island, IL 61201, USA.
  • Kane RR; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA ; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798, USA ; Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live Oak Street, Dallas
Tetrahedron Lett ; 56(2): 458-460, 2015 Jan 08.
Article em En | MEDLINE | ID: mdl-25601818
ABSTRACT
Protein conjugates of toll-like receptor 7 agonists have been shown to elicit powerful immune responses. In order to facilitate our studies in this area our group has developed efficient syntheses for a number of functionalized derivatives that retain immune stimulatory activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Tetrahedron Lett Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Tetrahedron Lett Ano de publicação: 2015 Tipo de documento: Article