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The bone morphogenetic protein system and the regulation of ovarian follicle development in mammals.
Rossi, Rodrigo O D S; Costa, José J N; Silva, Anderson W B; Saraiva, Márcia V A; Van den Hurk, Robert; Silva, José R V.
Afiliação
  • Rossi RO; Biotechnology Nucleus of Sobral - NUBIS,Federal University of Ceara,Sobral,CE,Brazil.
  • Costa JJ; Biotechnology Nucleus of Sobral - NUBIS,Federal University of Ceara,Sobral,CE,Brazil.
  • Silva AW; Biotechnology Nucleus of Sobral - NUBIS,Federal University of Ceara,Sobral,CE,Brazil.
  • Saraiva MV; Biotechnology Nucleus of Sobral - NUBIS,Federal University of Ceara,Sobral,CE,Brazil.
  • Van den Hurk R; Department of Pathobiology,Faculty of Veterinary Medicine,Utrecht University,PO Box 80.163,Utrecht,The Netherlands.
  • Silva JR; Biotechnology Nucleus of Sobral - NUBIS,Federal University of Ceara,Av. Comandante Maurocélio Rocha Ponte 100,CEP 62041-040,Sobral,CE,Brazil.
Zygote ; 24(1): 1-17, 2016 Feb.
Article em En | MEDLINE | ID: mdl-25613521
ABSTRACT
The bone morphogenetic protein (BMP) family consists of several growth factor proteins that belong to the transforming growth factor-ß (TGF-ß) superfamily. BMPs bind to type I and type II serine-threonine kinase receptors, and transduce signals through the Smad signalling pathway. BMPs have been identified in mammalian ovaries, and functional studies have shown that they are involved in the regulation of oogenesis and folliculogenesis. This review summarizes the role of the BMP system during formation, growth and maturation of ovarian follicles in mammals.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oogênese / Ovário / Proteínas Morfogenéticas Ósseas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Zygote Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oogênese / Ovário / Proteínas Morfogenéticas Ósseas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Zygote Ano de publicação: 2016 Tipo de documento: Article