The bone morphogenetic protein system and the regulation of ovarian follicle development in mammals.
Zygote
; 24(1): 1-17, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-25613521
ABSTRACT
The bone morphogenetic protein (BMP) family consists of several growth factor proteins that belong to the transforming growth factor-ß (TGF-ß) superfamily. BMPs bind to type I and type II serine-threonine kinase receptors, and transduce signals through the Smad signalling pathway. BMPs have been identified in mammalian ovaries, and functional studies have shown that they are involved in the regulation of oogenesis and folliculogenesis. This review summarizes the role of the BMP system during formation, growth and maturation of ovarian follicles in mammals.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oogênese
/
Ovário
/
Proteínas Morfogenéticas Ósseas
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Zygote
Ano de publicação:
2016
Tipo de documento:
Article