Cup-like blasts in acute myeloid leukemia.
Am J Hematol
; 90(9): 847-8, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-25615838
ABSTRACT
A patient with AML with normal karyotype and the cytological pattern of cup-like blasts (CLB) is reported. The typical morphology on Pappenheim stained blood smears is shown. In addition transmission electron microscopy pictures demonstrate impressively the invaginated nuclear pocket compressing the chromatin. Cup-like blasts usually do not express CD34. There is a close relationship of CLB-AML with the molecular aberrations of NPM1 and/or FLT3-ITD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células da Medula Óssea
/
Leucemia Mieloide Aguda
/
Núcleo Celular
Limite:
Aged80
/
Female
/
Humans
Idioma:
En
Revista:
Am J Hematol
Ano de publicação:
2015
Tipo de documento:
Article