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The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species.
Dicks, Matthew D J; Guzman, Efrain; Spencer, Alexandra J; Gilbert, Sarah C; Charleston, Bryan; Hill, Adrian V S; Cottingham, Matthew G.
Afiliação
  • Dicks MD; The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK. Electronic address: matthew.dicks@kcl.ac.uk.
  • Guzman E; The Pirbright Institute, Pirbright Laboratory, Pirbright, Surrey GU24 0NF, UK.
  • Spencer AJ; The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Gilbert SC; The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Charleston B; The Pirbright Institute, Pirbright Laboratory, Pirbright, Surrey GU24 0NF, UK.
  • Hill AV; The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Cottingham MG; The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK.
Vaccine ; 33(9): 1121-8, 2015 Feb 25.
Article em En | MEDLINE | ID: mdl-25629523

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Portadores de Fármacos / Vacinas Virais / Adenoviridae / Transgenes / Vetores Genéticos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Vaccine Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Portadores de Fármacos / Vacinas Virais / Adenoviridae / Transgenes / Vetores Genéticos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Vaccine Ano de publicação: 2015 Tipo de documento: Article