Assessment of long-term cognitive impairment after off-pump coronary-artery bypass grafting and related risk factors.
J Am Med Dir Assoc
; 16(3): 263.e9-11, 2015 Mar.
Article
em En
| MEDLINE
| ID: mdl-25648462
ABSTRACT
OBJECTIVES:
To assess cognitive impairment after off-pump coronary-artery bypass grafting, with a particular emphasis on long-term follow-up and related risk factors.DESIGN:
Prospective study.SETTING:
Virgen de la Victoria University Hospital, Málaga, Spain.PARTICIPANTS:
Participants were 36 patients undergoing off-pump coronary-artery bypass grafting. MEASUREMENTS Changes in the neuropsychological test battery administered from before to after surgery (1, 6, and 12 months). Postoperative cognitive impairment was defined by a significant decrease.RESULTS:
A significantly multidomain (attention-executive functions, P < .01; immediate and delayed memory, P < .001; and verbal fluency, P < .05) postoperative cognitive impairment was shown, being maximum at 6 months (more than 50% of patients) and still presented at 12 months (more than 30% of patients), but partially recovered. Related risk factors as smoking (P < .01), diabetes mellitus (P < .01), peripheral arteriopathy (P < .01), obesity (P < .05), lower hematocrit (P < .01), and hemoglobin (P < .05) levels and diastolic blood pressure (P < .05) were identified as predictors of cognitive impairment. Better New York Heart Association class (P < .01) and less severity of angina (P < .01) were associated with partial postoperative recovering.CONCLUSION:
A multidomain long-term postoperative cognitive impairment and a partial neurocognitive recovering were detected after off-pump coronary-artery bypass grafting and were associated with several nonspecific surgery factors. These findings may be useful when counseling patients before surgery and suggest the importance of long-term neurocognitive evaluation.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Procedimentos Cirúrgicos Eletivos
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Transtornos Cognitivos
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Estenose Coronária
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Ponte de Artéria Coronária sem Circulação Extracorpórea
Tipo de estudo:
Etiology_studies
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Evaluation_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
J Am Med Dir Assoc
Ano de publicação:
2015
Tipo de documento:
Article