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Timosaponin AIII and its metabolite sarsasapogenin ameliorate colitis in mice by inhibiting NF-κB and MAPK activation and restoring Th17/Treg cell balance.
Lim, Su-Min; Jeong, Jin-Ju; Kang, Geum-Dan; Kim, Kyung-Ah; Choi, Hyun-Sik; Kim, Dong-Hyun.
Afiliação
  • Lim SM; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
  • Jeong JJ; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
  • Kang GD; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
  • Kim KA; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Republic of Korea.
  • Choi HS; Dongwha Pharm Research Institute, 71, Tapsil-ro, 35beon-gil, Giheung-gu, Yongin-si, Gyeonggi-do 446-902, Republic of Korea.
  • Kim DH; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Republic of Korea. Electronic address: dhkim@khu.ac.kr.
Int Immunopharmacol ; 25(2): 493-503, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25698557
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saponinas / Espirostanos / Esteroides / Colite / Anti-Inflamatórios Idioma: En Revista: Int Immunopharmacol Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saponinas / Espirostanos / Esteroides / Colite / Anti-Inflamatórios Idioma: En Revista: Int Immunopharmacol Ano de publicação: 2015 Tipo de documento: Article