A crosstalk between chromatin remodeling and histone H3K4 methyltransferase complexes in endothelial cells regulates angiotensin II-induced cardiac hypertrophy.

Weng, Xinyu; Yu, Liming; Liang, Peng; Li, Luyang; Dai, Xin; Zhou, Bisheng; Wu, Xiaoyan; Xu, Huihui; Fang, Mingming; Chen, Qi; Xu, Yong

Weng, Xinyu; Yu, Liming; Liang, Peng; Li, Luyang; Dai, Xin; Zhou, Bisheng; Wu, Xiaoyan; Xu, Huihui; Fang, Mingming; Chen, Qi; Xu, Yong.

Afiliação

Weng X; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Yu L; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Liang P; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Li L; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Dai X; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Zhou B; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Wu X; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Xu H; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Fang M; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China; Department of Nursing, Jiangsu Jiankang Vocational University, Nanjing, China. Electronic address: mmfangnjmu@yahoo.com.
Chen Q; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Xu Y; Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China. Electronic address: yxu2005@gmail.com.

J Mol Cell Cardiol ; 82: 48-58, 2015 May.

Article em En | MEDLINE | ID: mdl-25712920

Assuntos

Angiotensina II/metabolismo; Cardiomegalia/genética; Cardiomegalia/metabolismo; Montagem e Desmontagem da Cromatina; Células Endoteliais/metabolismo; Histona-Lisina N-Metiltransferase/metabolismo; Animais; Cardiomegalia/patologia; Linhagem Celular Transformada; DNA Helicases/metabolismo; Modelos Animais de Doenças; Endotelina-1/genética; Endotelina-1/metabolismo; Histona Metiltransferases; Humanos; Masculino; Camundongos; Proteínas Nucleares/metabolismo; Regiões Promotoras Genéticas; Ligação Proteica; Transdução de Sinais; Transativadores/metabolismo; Fatores de Transcrição/metabolismo

Palavras-chave

Cardiac hypertrophy; ET-1; Epigenetics; Transcriptional regulation; Vascular endothelial cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angiotensina II / Histona-Lisina N-Metiltransferase / Cardiomegalia / Células Endoteliais / Montagem e Desmontagem da Cromatina Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2015 Tipo de documento: Article

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