Dronedarone and digitalis: individually reduced post-repolarization refractoriness enhances life-threatening arrhythmias.

Frommeyer, Gerrit; Milberg, Peter; Schulze Grotthoff, Jochen; Dechering, Dirk G; Kochhäuser, Simon; Stypmann, Jörg; Fehr, Michael; Breithardt, Günter; Eckardt, Lars

Frommeyer, Gerrit; Milberg, Peter; Schulze Grotthoff, Jochen; Dechering, Dirk G; Kochhäuser, Simon; Stypmann, Jörg; Fehr, Michael; Breithardt, Günter; Eckardt, Lars.

Afiliação

Frommeyer G; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany gerrit.frommeyer@ukmuenster.de.
Milberg P; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Schulze Grotthoff J; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Dechering DG; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Kochhäuser S; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Stypmann J; Division of Cardiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Fehr M; Clinic of Exotic Pets, Reptiles, Exotic and Feral Birds, University of Hanover, Hanover, Germany.
Breithardt G; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
Eckardt L; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.

Europace ; 17(8): 1300-8, 2015 Aug.

Article em En | MEDLINE | ID: mdl-25713011

Assuntos

Amiodarona/análogos & derivados; Glicosídeos Digitálicos/administração & dosagem; Glicosídeos Digitálicos/efeitos adversos; Fibrilação Ventricular/induzido quimicamente; Fibrilação Ventricular/prevenção & controle; Amiodarona/administração & dosagem; Amiodarona/efeitos adversos; Animais; Antiarrítmicos/administração & dosagem; Antiarrítmicos/efeitos adversos; Dronedarona; Interações Medicamentosas; Sinergismo Farmacológico; Quimioterapia Combinada; Feminino; Coelhos; Fibrilação Ventricular/diagnóstico

Palavras-chave

Digitalis; Dronedarone; Ouabain; Post-repolarization refractoriness; Therapeutic safety; Ventricular fibrillation

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Fibrilação Ventricular / Glicosídeos Digitálicos / Amiodarona Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Europace Ano de publicação: 2015 Tipo de documento: Article

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