The role of the miR-31/FIH1 pathway in TGF-ß-induced liver fibrosis.

Hu, Jiangfeng; Chen, Chao; Liu, Qidong; Liu, Baohai; Song, Chenlin; Zhu, Songchen; Wu, Chaoqun; Liu, Su; Yu, Hongyu; Yao, Dingkang; Kang, Jiuhong; Zhu, Liang

Hu, Jiangfeng; Chen, Chao; Liu, Qidong; Liu, Baohai; Song, Chenlin; Zhu, Songchen; Wu, Chaoqun; Liu, Su; Yu, Hongyu; Yao, Dingkang; Kang, Jiuhong; Zhu, Liang.

Afiliação

Hu J; *Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Chen C; Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Liu Q; §Clinical and Translational Research Centre of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signalling and Disease Research, School of Life Science and Technology, Tongji University, Shanghai, China.
Liu B; âOffice of Medical Education, Training Department, Second Military Medical University, Shanghai, China.
Song C; ¶German Cancer Research Centre, Heidelberg, Germany.
Zhu S; §Clinical and Translational Research Centre of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signalling and Disease Research, School of Life Science and Technology, Tongji University, Shanghai, China.
Wu C; **Genetics Institute, Fudan University, Shanghai, China.
Liu S; Department of Gastroenterology, Central Hospital of Zhabei District, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Yu H; Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Yao D; *Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Kang J; §Clinical and Translational Research Centre of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signalling and Disease Research, School of Life Science and Technology, Tongji University, Shanghai, China.
Zhu L; *Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China.

Clin Sci (Lond) ; 129(4): 305-17, 2015 Aug.

Article em En | MEDLINE | ID: mdl-25728779

Assuntos

Células Estreladas do Fígado/efeitos dos fármacos; Cirrose Hepática Experimental/metabolismo; Fígado/efeitos dos fármacos; MicroRNAs/metabolismo; Oxigenases de Função Mista/metabolismo; Proteínas Repressoras/metabolismo; Fator de Crescimento Transformador beta1/farmacologia; Regiões 3' não Traduzidas; Animais; Sítios de Ligação; Movimento Celular; Proliferação de Células; Genes Reporter; Células HEK293; Células Estreladas do Fígado/metabolismo; Células Estreladas do Fígado/patologia; Humanos; Fígado/metabolismo; Fígado/patologia; Cirrose Hepática Experimental/genética; Cirrose Hepática Experimental/patologia; Masculino; Metaloproteinase 2 da Matriz/metabolismo; Camundongos; MicroRNAs/genética; Oxigenases de Função Mista/genética; Interferência de RNA; Ratos; Proteínas Repressoras/genética; Transdução de Sinais/efeitos dos fármacos; Proteína Smad3/metabolismo; Transfecção; Regulação para Cima

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / MicroRNAs / Fator de Crescimento Transformador beta1 / Células Estreladas do Fígado / Oxigenases de Função Mista / Fígado / Cirrose Hepática Experimental Limite: Animals / Humans / Male Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google