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Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis.
Chen, Sidi; Sanjana, Neville E; Zheng, Kaijie; Shalem, Ophir; Lee, Kyungheon; Shi, Xi; Scott, David A; Song, Jun; Pan, Jen Q; Weissleder, Ralph; Lee, Hakho; Zhang, Feng; Sharp, Phillip A.
Afiliação
  • Chen S; David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Sanjana NE; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute
  • Zheng K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA.
  • Shalem O; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA.
  • Lee K; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Shi X; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA.
  • Scott DA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA.
  • Song J; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Pan JQ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA.
  • Weissleder R; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Lee H; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Cambridge, MA 02142, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute
  • Sharp PA; David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: sharppa@mit.edu.
Cell ; 160(6): 1246-60, 2015 Mar 12.
Article em En | MEDLINE | ID: mdl-25748654
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Técnicas de Inativação de Genes / Sistemas CRISPR-Cas / Neoplasias Pulmonares / Metástase Neoplásica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Técnicas de Inativação de Genes / Sistemas CRISPR-Cas / Neoplasias Pulmonares / Metástase Neoplásica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2015 Tipo de documento: Article