Development of a time-resolved fluorescence probe for evaluation of competitive binding to the cholecystokinin 2 receptor.

Elshan, N G R Dayan; Jayasundera, Thanuja; Weber, Craig S; Lynch, Ronald M; Mash, Eugene A

Elshan, N G R Dayan; Jayasundera, Thanuja; Weber, Craig S; Lynch, Ronald M; Mash, Eugene A.

Afiliação

Elshan NG; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0041, USA.
Jayasundera T; Department of Physiology, University of Arizona, Tucson, AZ 85724-5051, USA.
Weber CS; Department of Physiology, University of Arizona, Tucson, AZ 85724-5051, USA.
Lynch RM; Department of Physiology, University of Arizona, Tucson, AZ 85724-5051, USA; The Bio5 Institute, University of Arizona, Tucson, AZ 85721-0240, USA.
Mash EA; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0041, USA. Electronic address: emash@email.arizona.edu.

Bioorg Med Chem ; 23(8): 1841-8, 2015 Apr 15.

Article em En | MEDLINE | ID: mdl-25769518

Assuntos

Corantes Fluorescentes/química; Corantes Fluorescentes/metabolismo; Receptor de Colecistocinina B/metabolismo; Ligação Competitiva; Corantes Fluorescentes/síntese química; Células HEK293; Humanos; Espectrometria de Fluorescência

Palavras-chave

Cholecystokinin 2 receptor; Dissociation-enhanced lanthanide fluoroimmunoassay; High-throughput screening; Multivalent binding; Time-resolved fluorescence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor de Colecistocinina B / Corantes Fluorescentes Limite: Humans Idioma: En Revista: Bioorg Med Chem Ano de publicação: 2015 Tipo de documento: Article

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