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Combined N-of-1 trials to investigate mexiletine in non-dystrophic myotonia using a Bayesian approach; study rationale and protocol.
Stunnenberg, Bas C; Woertman, Willem; Raaphorst, Joost; Statland, Jeffrey M; Griggs, Robert C; Timmermans, Janneke; Saris, Christiaan G; Schouwenberg, Bas J; Groenewoud, Hans M; Stegeman, Dick F; van Engelen, Baziel G M; Drost, Gea; van der Wilt, Gert Jan.
Afiliação
  • Stunnenberg BC; Department of Neurology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Bas.Stunnenberg@Radboudumc.nl.
  • Woertman W; Department of Health Evidence, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Willem.Woertman@Radboudumc.nl.
  • Raaphorst J; Department of Neurology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Joost.Raaphorst@Radboudumc.nl.
  • Statland JM; Department of Neurology, University of Kansas Medical Center, PO Box 2012, KS 66160, Kansas City, USA. JStatland@kumc.edu.
  • Griggs RC; Department of Neurology, University of Rochester Medical Center, PO Box 420669, Rochester, NY, 14642, USA. Robert_Griggs@URMC.Rochester.edu.
  • Timmermans J; Department of Cardiology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Janneke.Timmermans@Radboudumc.nl.
  • Saris CG; Department of Neurology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Christiaan.Saris@Radboudumc.nl.
  • Schouwenberg BJ; Department of Pharmacology-Toxicology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Bas.Schouwenberg@Radboudumc.nl.
  • Groenewoud HM; Department of Health Evidence, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Hans.Groenewoud@Radboudumc.nl.
  • Stegeman DF; Department of Neurology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Dick.Stegeman@Radboudumc.nl.
  • van Engelen BG; Department of Neurology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Baziel.vanEngelen@Radboudumc.nl.
  • Drost G; Department of Neurology and Neurosurgery, University Medical Center Groningen, PO Box 30001, 9700 RB, Groningen, The Netherlands. Gea.Drost@umcg.nl.
  • van der Wilt GJ; Department of Health Evidence, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. GertJan.vanderWilt@Radboudumc.nl.
BMC Neurol ; 15: 43, 2015 Mar 25.
Article em En | MEDLINE | ID: mdl-25880166

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Teorema de Bayes / Doenças Raras / Mexiletina / Miotonia Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Neurol Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Teorema de Bayes / Doenças Raras / Mexiletina / Miotonia Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Neurol Ano de publicação: 2015 Tipo de documento: Article