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[Extract of Hirudo medicinalis leeches: biogenic substance for the creation of effective drugs].
Eksp Klin Farmakol ; 78(2): 15-9, 2015.
Article em Ru | MEDLINE | ID: mdl-25898542
ABSTRACT
Investigations of the extract of medicinal leech Girulux established parameters that enable one to verify the authenticity of related drugs using the characteristics of their UV spectra the and anticoagulant and antithrombin activity. The limits of pH must range from 5.5 to 7.5. Pilot-scale series of medical leech extract are in compliance with terms of "microbiological purity" quality characteristics. The natural storage has been used to assess the temporal stability of leech extract. The obtained characteristics showed that the activity of extract was retained after 3-year storage.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Misturas Complexas / Hirudo medicinalis / Inibidores Enzimáticos / Fibrinolíticos / Anticoagulantes Limite: Animals Idioma: Ru Revista: Eksp Klin Farmakol Ano de publicação: 2015 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Misturas Complexas / Hirudo medicinalis / Inibidores Enzimáticos / Fibrinolíticos / Anticoagulantes Limite: Animals Idioma: Ru Revista: Eksp Klin Farmakol Ano de publicação: 2015 Tipo de documento: Article