Genetic modification of ALAD and VDR on lead-induced impairment of hearing in children.

Pawlas, Natalia; Broberg, Karin; Olewinska, Elzbieta; Kozlowska, Agnieszka; Skerfving, Staffan; Pawlas, Krystyna

Pawlas, Natalia; Broberg, Karin; Olewinska, Elzbieta; Kozlowska, Agnieszka; Skerfving, Staffan; Pawlas, Krystyna.

Afiliação

Pawlas N; Institute of Occupational Medicine and Environmental Health, PL 41-200 Sosnowiec, Poland. Electronic address: n-pawlas@wp.pl.
Broberg K; Division of Occupational and Environmental Medicine, Lund University, SE-22185 Lund, Sweden; Unit of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Olewinska E; Institute of Occupational Medicine and Environmental Health, PL 41-200 Sosnowiec, Poland.
Kozlowska A; Institute of Occupational Medicine and Environmental Health, PL 41-200 Sosnowiec, Poland.
Skerfving S; Division of Occupational and Environmental Medicine, Lund University, SE-22185 Lund, Sweden.
Pawlas K; Institute of Occupational Medicine and Environmental Health, PL 41-200 Sosnowiec, Poland; Department of Hygiene, Wroclaw Medical University, PL 50-368 Wroclaw, Poland.

Environ Toxicol Pharmacol ; 39(3): 1091-8, 2015 May.

Article em En | MEDLINE | ID: mdl-25899472

Assuntos

Perda Auditiva/fisiopatologia; Chumbo/sangue; Polimorfismo Genético; Sintase do Porfobilinogênio/genética; Receptores de Calcitriol/genética; Adolescente; Criança; Pré-Escolar; Potenciais Evocados Auditivos do Tronco Encefálico; Feminino; Perda Auditiva/sangue; Perda Auditiva/etiologia; Perda Auditiva/genética; Testes Auditivos; Humanos; Chumbo/toxicidade; Masculino

Palavras-chave

ALAD polymorphism; Brainstem auditory evoked potential; Geneenvironment interaction; Lead; Neurotoxicity; Otoemission; Pure-tone audiometry; VDR polymorphism; rs1139488; rs1544410; rs1800435; rs2228570; rs731236

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Receptores de Calcitriol / Sintase do Porfobilinogênio / Perda Auditiva / Chumbo Tipo de estudo: Etiology_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Environ Toxicol Pharmacol Ano de publicação: 2015 Tipo de documento: Article

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