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Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease.
Li, Alexander H; Morrison, Alanna C; Kovar, Christie; Cupples, L Adrienne; Brody, Jennifer A; Polfus, Linda M; Yu, Bing; Metcalf, Ginger; Muzny, Donna; Veeraraghavan, Narayanan; Liu, Xiaoming; Lumley, Thomas; Mosley, Thomas H; Gibbs, Richard A; Boerwinkle, Eric.
Afiliação
  • Li AH; Human Genetics Center, University of Texas Health Science Center, Houston, Texas, USA.
  • Morrison AC; Human Genetics Center, University of Texas Health Science Center, Houston, Texas, USA.
  • Kovar C; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Cupples LA; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts, USA. [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
  • Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
  • Polfus LM; Human Genetics Center, University of Texas Health Science Center, Houston, Texas, USA.
  • Yu B; Human Genetics Center, University of Texas Health Science Center, Houston, Texas, USA.
  • Metcalf G; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Muzny D; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Veeraraghavan N; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Liu X; Human Genetics Center, University of Texas Health Science Center, Houston, Texas, USA.
  • Lumley T; 1] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA. [2] Department of Statistics, University of Auckland, Auckland, New Zealand.
  • Mosley TH; Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, USA.
  • Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Boerwinkle E; 1] Human Genetics Center, University of Texas Health Science Center, Houston, Texas, USA. [2] Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Nat Genet ; 47(6): 640-2, 2015 Jun.
Article em En | MEDLINE | ID: mdl-25915599

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aterosclerose / Loci Gênicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Genet Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aterosclerose / Loci Gênicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Genet Ano de publicação: 2015 Tipo de documento: Article