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IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.
Wan, Xiaolin; Yeung, Choh; Heske, Christine; Mendoza, Arnulfo; Helman, Lee J.
Afiliação
  • Wan X; Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: xiaolinw@mail.nih.gov.
  • Yeung C; Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Heske C; Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Mendoza A; Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Helman LJ; Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: helmanl@nih.gov.
Neoplasia ; 17(4): 358-66, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25925378
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Receptor IGF Tipo 1 / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-yes Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Neoplasia Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Receptor IGF Tipo 1 / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-yes Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Neoplasia Ano de publicação: 2015 Tipo de documento: Article